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EcoRI digests one site in the transgene; thus, the transgene in the transgenic mice was integrated in a head-to-tail configuration.
Furthermore, the U-4-11.1 U-4-11.1 U-4-11.1hich was derived from the U-4-11 U3 putativesolated froMuERV lung of burn mice), whichntegrated near a cluster of immunoglobulin gamma (IgG) Fc receptor genes.
In addition, the L-1-1.8 putative MuERV derived from the L-1-1 U3 probe (isolated from the liver of no burn mice) was integrated between exon 2 and 3 of chromosome domain-helicase-DNA-binding protein 9 (CHD9), a chromosome remodelling factor [ 44, 45].
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BL/6N mice were integrated in our studies as Strekalova et al. [25] showed an association of anhedonic and depressive-like behaviour for a subgroup of this mouse strain after chronic stress.
Since abundant TSS data for human and mouse were integrated into DBTSS, large scale cross-species comparisons of promoter regions became possible [ 30, 31].
HBx gene was integrated into the mouse p21 locus.
The targeting construct carrying mouse S112A mutant Yap1 followed by IRES-GFP was integrated into Gt ROSA)26Sor (Rosa26 ) locus.
(C ) The High CpG / Low G + C construct was integrated into Dnmt 3a −/− Dnmt 3b−/− double mutant mouse ES cells.
The lighting was integrated into the building.
Omaha's Fire Department was integrated in 1957.
The examples will highlight possible ways genetically altered mice may be integrated into a comprehensive research and testing strategy and thereby provide an improved estimation of human health risks.
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