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Furthermore, the highly increased neutrophilic influx in the liver from septic WT mice was indicated by MPO staining (Fig. 5c).

Activation by inflammatory stimuli after antibody transfer to the mice was indicated by increases in leukocyte rolling along and attachment to the venular endothelium.

Reduced inflammation in these mice was indicated by decreased TNFα and IL-1β colonic expression following netrin-1 treatment (figure 5E F).

Hyperactivity of the HPA axis in INI mice was indicated by their elevated nadir levels of plasma corticosterone and increased morning expression of CRH mRNA in the paraventricular nucleus of the hypothalamus.

A hypercontractile systolic function in db/db mice was indicated by a greater fractional shortening and larger ejection fraction (db/+: 67 ± 2 versus db/db: 75 ± 1%; n = 6, P < 0.05).

Vessel wall remodeling in dox-induced mice was indicated by fragmentation of the elastic lamellae in the tunica media layer of anterior vessels including carotid artery, aortic arch, and thoracic aorta (Fig. 1F H).

The impacts of CMZ, vitamin C, and their combination on the serum level of total protein and LDH in Swiss albino mice are indicated in Tables 7 and 8, respectively.

Wild-type product size was 400 bp whereas Het mice were indicated by a band at 640 bp.

The genotypes of the mice are indicated.

Numbers of mice are indicated in the histogram.

Numbers of observed and expected (in parenthesis) wild-type, heterozygote and homozygote mice are indicated.