Serum α-gal A activity of 10-week-old Fabry mice was increased in LV/α-gal A-injected animals compared to controls.
The MHC class II expression on PLN B cells from CY-treated NOD mice was increased compared with that from control NOD mice (Figure 2B).
The brain HA production in the 3xTg-AD mice was increased by feeding them with a vitamin B6-deficient diet for 3 weeks.
β-cell apoptosis in Hq mutant mice was increased at all ages compared to WT (Neonates P0: 0.4% in Hq mutant mice versus 0.2% in WT.
The spleen weight in uninfected mice was increased in HFD-fed mice compared with LFD-fed mice (P = 0.04, Fig. 7A).
Interestingly, the amount of PrPSc incorporated by suckling SCID mice was increased when immunoglobulin G (IgG) was administered orally together with PrPSc.
Bradykinin receptor importance on survival was also analyzed and mortality of B2KO mice was increased at 120h post ischemia (Figure 2A).
Furthermore, the amount of IFN-γ produced by HSP70- and PG-specific cells from HSP70 treated mice was increased (Fig. 4C).
Three hours after re-feeding, the insulin levels of normal animals rose by nearly 30 times whereas the rise in SirT1-null mice was increased only 10 fold (Figure 3D).
After feeding the animals a high fat, high cholesterol diet for 9 weeks, plasma PLTP activity in both LDLR−/− and LDLR−/−/huPLTPtg/wt mice was increased by about 2-fold when compared to chow fed animals of the same genotype.
Conversely, peripheral parasitemia in infected COX-1 null mice was increased 9.2 fold compared to WT littermates with peak parasitemia increased 5.7 fold and prolongation of parasite levels from 33 dpi to 42 dpi.
