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Additional evidence lending support to Rac1 deletion causing failure of thymic ontogeny seen in the K5CrexRac1flox/flox mice was gained by using heterotopic transplantation of embryonic thymic cells from the K14CreERxRac1flox/flox mice.
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Of more interest, ZEB1 haploinsufficiency independently reduces glucose uptake during part of the time when the mice are gaining excessive weight while on a HFD.
He did not promise that the mouse would say anything in reply, doubtless because a great many genes must have undergone evolutionary change to endow people with the faculty of language, and the new mouse was gaining only one of them.
If you've ever tried to clean out the insides of a PC mouse, you'll understand why the optical mouse is gaining popularity around the world.
The cat-and-mouse substrip was gaining in popularity; instead of filling up space in the bottom of The Dingbat Familys panels, it began to occupy a tier of panels of its own.
New structural insights into the active sites of the human and mouse enzymes were gained.
Information on mouse knockout phenotypes were gained from the Mouse Genome Informatics site (http://www.informatics.jax.org, accessed on 1/12/2010) [ 27].
This indicates that the DY genes were lost in human and mouse rather than being gained in other mammals.
Even though they were consuming exactly the same number of calories as lean mice, they were gaining weight.
Insights into differential germline gene expression and tumorigenesis have been gained mainly from mice models, such as the overexpression of the RAS family of genes [ 43], Mad2 [ 44] or c-MYC [ 45, 46].
Evidence for the role of IGFs in this process has been gained from transgenic mouse models.
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