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The localization efficiency of liposomes in tumor tissues of the live tumor-bearing mice was directly observed under a fluorescence microscope (Macro-Imaging System Plus LT-9macimstsplus, Lightools Research, Encinitas, CA, USA) equipped with Image-Pro Plusoftwarere (Media Cybernetics, Silver Spring, MD, USA).
We found that the fat content of livers of our male mice was directly proportional to their % body fat.
In addition, clinical improvement of EAE mice was directly associated with suppressed inflammation and reduced amounts of disease-related CD4+ T cell infiltrates in CNS of Lacto-mix-treated mice.
Survival of FVB/NJ- Ugt1−/− mice was directly related to the extent of PT treatment.
As expected, survival of mutant mice was directly related to the extent of PT treatment (Fig. 3B).
Peripheral whole blood from control mice was directly obtained by puncture of the caudal vein and immediately processed for further analyses.
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In all cases, 2, 4 and 8 month-old transgenic mice were directly compared with age-matched non-transgenic (wild-type) litter mates.
The pentobarbital induced sleeping time in mice is directly proportionate to the CNS depressant activity.
Antibodies present in the serum of arthritic KRN mice are directly pathogenic upon systemic transfer.
It is likely that the reported different tumorigenic properties in SCID mice are directly linked their genomic alterations.
Of interest, arthritis in hTNFtg mice is directly induced by overexpression of TNF, a potent trigger of the JNK pathway.
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