We noted that the frequency of Cre-mediated deletion of the floxed Cdc25A allele in the small intestines of tamoxifen-treated mice was comparable for each genotype (compare Fig. 2C and Fig. 4).
Biodistribution in normal mice was comparable to literature data.
Moreover, the memory loss in mice was comparable to the degree of amnesia produced by scopolamine, a control amnesic agent.
The concentration of these cytokines in the blood of RNF13-KO mice was comparable to that in WT mice (Fig. 4C).
The total number of infiltrated granulocytes (CD11b+Ly6Ghi) in the fibrotic kidney of the RBP-J cKO mice was comparable with that of the control (Fig. S4B).
The metabolic stability of [11C]1 and [18F]2 in SCID mice was comparable to the previously reported stability in Wistar rats.
FACS analysis showed that while the percentage of proliferating macrophages was significantly higher in the fibrotic kidney as compared with the contralateral kidney, the absolute number of BrdU+F4/80+ macrophages in the fibrotic kidneys of RBP-J cKO mice was comparable with that of the control (Fig. 4A and 4B).
The researchers found the suppression of beta-amyloid production to be greater at larger doses of citalopram, but the most effective dose tested on mice was comparable to a 50-mg dose of citalopram, a dose that is substantially higher than that commonly used to treat those with depression.
Nevertheless, adenylyl cyclase activity in brown adipose from AC3−/− and AC3+/+ mice was comparable (Figure S3B).
The number of axons in 60-day-old mice was comparable to that in control mice (102.5±7%, n = 6).
Noteworthy, the magnitude of T cell responses in DRAG mice was comparable to that of human PBMCs from healthy volunteers.
