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The exaggerated lipid accumulation in sucrose-palmitate-fed mice was attributable to a disproportionate rise in hepatic de novo lipogenesis.
Taken together, our data suggested that the reduced body weight of Rcan2−/− mice was attributable to reduced food intake.
Once again the parasite burden was lower in BALB/c mice confirming that the poor expansion of P.berghei in BALB/c mice was attributable to intra-hepatic factors.
Similarly, the weight difference between female AC3−/− and AC3+/+ mice was attributable to a large increase in fat mass (Figure 2B).
To determine whether the strain difference in SI between early-adolescent mice was attributable to the genetic background of the test mouse, we conducted a series of control experiments in which PD 30/31 males were given an opportunity to investigate age-matched females after 24 hrs of social isolation.
Second, we demonstrate that inhibition of tumour growth in EBOEC-injected mice was attributable to the inhibitory effect of endostatin on tumour angiogenesis.
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The increased memory cells in Cdc42−/− mice are attributable to enhanced proliferative renewal.
It can be concluded that the severe and identical clinical phenotype in both humans and mice is attributable to the complete absence of the CD18 protein.
These results suggest that the lung phenotype of Cby−/− mice is attributable, at least in part, to reduced proliferation rather than increased apoptosis or alveolar septation defects.
Together with our control experiments (see Experiments 2 6), the data strongly suggest that strain-dependent variation in the social approach phenotypes of early-adolescent mice is attributable to a genetic influence on a specific, social-motivational process.
To determine whether the reduction in contextual fear memory of neurabin KO mice is attributable to changes in pain sensitivity to the foot shock, we measured acute sensory thresholds in the hotplate and tail-flick tests.
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