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In contrast, at 8 10 weeks of age glucose tolerance in both male and female dmpk−/− mice was altered (Fig. 3 B and C, respectively).
Furthermore, expression of mRNA for several cytoskeleton-related proteins in the medial striatum of B6CBAF1/J mice was altered by acute morphine administration [ 18].
We also examined whether ERK-1/2 signaling, which has been shown to play a role in the susceptibility to CVB3-induced myocarditis in mice, was altered [ 15].
We observed that the BALT in CCR7-/ mice was altered during the course of BLM-induced injury, and may represent the dynamics of Treg trafficking during BLM-induced pulmonary remodeling.
Regardless, however, the number of cells positive for both LacZ and Ki67 in the DG and VZ/SVZ of IGF1RNestin−KO mice was altered in a pattern similar to LacZ+ cells or Ki67+ cells, being ∼30%and∼63%3% of that in controls respectively (Table 1).
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Further, Akt/GSK3/cyclin D1 signaling pathways in the liver of treated mice were altered, which may help prevent homocysteine-induced cell cycle dysfunction.
These results show that anxiety-related behaviors of SCR mice were altered.
In cortex, 566 (wildtype mice) and 623 (APP23 mice) spots were altered and in hippocampus, 571 (wildtype mice) and 672 spots (APP23 mice) were altered, respectively.
These results suggest that 5-HT signaling in the brains of patDp/+ mice is altered during these developmental stages.
One hypothesis is that the PrPC expression pattern in Tga20 mice is altered due to the deletion of the large intron from the PrP gene construct.
It would be interesting to determine whether cataract development in αB-R120G knock-in mice is altered in mouse strains that have the full complement of the beaded filaments.
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