Sentence examples for mice vulnerable to from inspiring English sources

Ovariectomy downregulates glutaredoxin and renders female mice vulnerable to l-BOAA toxicity as evidenced by activation of AP1, loss of GSH and complex I activity indicating the important role of glutaredoxin in neuroprotection.

Therefore, our findings suggest the interesting possibility that loss of Splunc1 function might render Splunc1 –/– mice vulnerable to otitis through multiple overlapping mechanisms.

Experts testing the neurotoxicity of the pool-derived substances in animals with respect to scoliosis may wish to consider including mice vulnerable to scoliosis to establish whether, and if so, where in the CNS, the neurotoxic substances may become localised.

Dr. Guarente said he was looking into whether extra sirtuin had an effect in mice made vulnerable to Parkinson's and Huntington's disease.

Remarkably, however, male tfm mice were vulnerable to Lef1 haploinsufficiency, similar to females (Figure 5).

Our model using an outbred strain may recapitulate the variability described by Nonogaki and coworkers and suggests that at the "population" level, male mice are vulnerable to obesity only when faced with HFD.

On the other hand, GSK-3β also functions as a negative regulator of pro-inflammatory cytokine expression [92], [93] and decreased GSK-3β expression may render Pink1−/− mice more vulnerable to TNF-α, IL-1β and LPS-induced brain inflammation [88], [91], [94].

And Liu et al. (2011) demonstrated that cortical neurons isolated from OGG1-deficient mice were more vulnerable to oxidative stress than that of normal OGG1 mice, and OGG1-deficient mice developed cortical infarcts and behavior deficits after cerebral artery occlusion [ 33].

Nitric oxide synthase (iNOs) mutant mice are more vulnerable to some types of infection than wild-type mice [ 21].

While these studies have concluded that female mice are more vulnerable to AD-related deficits, we offer two additional interpretations: in mouse models of AD, 1) female gonadal hormones are more deleterious in female brains than male hormones in male brains or 2) male gonadal hormones are more beneficial in male brains than female hormones in female brains.

A recent report showed that disruption of AdipoR1 and AdipoR2 in mice caused the mice to be more vulnerable to insulin resistance than adiponectin-knockout mice.