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Figure 2 (left part) illustrates the tissue-activity curves (TACs) extracted from the dynamic images of seven mice using two circular VOIs manually delineated on the tumor as well as an equal size VOI on the contralateral striatum.
A protocol is described for the simple, rapid, and reproducible laser microdissection of brain regions and sub-regions for microarray-based gene expression analyses from individual rats or mice using two rounds of in vitro transcription (IVT).
An experimental infection with AHSV-4 was conducted in IFNAR −/− mice using two different virus dose levels.
The effects of nicorandil on cardiac disease were examined in R120G TG mice using two different protocols.
In an attempt to avoid this difficulty, we investigated the persistence of diet-induced obesity in male C57BL/6 mice using two different high energy diets to generate varying degrees of weight gain before simultaneously switching to ad libitum chow to determine whether diet-induced obesity would be reversed.
A previously described protocol [16] was used to train and test mice using two clear-plastic conditioning chambers (26×18×18 cm high) (Med-Associates, St . Albans VT) which were easily distinguished by different olfactory, visual, and tactile cues present in each chamber.
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This study aims at evaluating two clinically available 99mTc-labeled myocardial perfusion tracers (99mTc-sestamibi vs. 99mTc-Tetrofosmin) in mice using four different imaging protocols.
Immunogenicity studies and fertility trials were performed in outbred Swiss Webster mice using four ZP2 constructs: Val35 Gly200 (ZP2Val35 Leu331al35–Leu331 (ZPro325 Ala637Pro325–and637 (ZP2P325–A637), and Val35 Ala637 (ZP2Val35 Ala637
The sera from rabbits immunized with a combination of the four recombinant toxins were collected separately and used to assess their neutralization capacity in vitro (pre-incubating the serum with the respective scorpion venom and injecting the mixture into mice), using six mice for each serum/venom combination tested.
The two models were here modified to simulate education in single MHC class I mice, using three Ly49 receptor with known pre-education frequencies, and a fourth receptor with unknown pre-education frequency.
In the present study, several compounds affecting anxiety were assayed on ABP/Le and C57BL/6/ByJ mice using three behavioural models of anxiety: the elevated plus-maze, the light-dark discrimination test and the free exploratory paradigm.
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