Finally, a hypoglycemic assay was conducted in mice, using the best formulation.
Behavioral effects were investigated in mice using the elevated plus-maze.
To address this issue, we generated endothelial-specific CD146 knockout (CD146EC-KO) mice using the Tg(Tek-cre) system.
To gain a better understanding of the angiogenic functions of CD146 in vivo, we generated endothelial CD146 knockout (CD146EC-KO) mice using the Tg(Tek-cre) system.
(E, F) Serum IL-1β was determined in WT and Nlrp3 KO mice using the Abcam kit according to the manufacturer's protocol.
The in vivo therapeutic effect was evaluated in nude NMRI mice using the sPLA2 secreting mammary carcinoma cell line MT-3.
Imaging in live mice using the Xenogen IVIS system demonstrated that the K6a-specific siRNA strongly inhibited bicistronic K6a-luciferase gene expression in vivo.
Preliminary pulmonary transfection of mice using the degradable nanoparticles demonstrated a remarkably higher expression of firefly luciferase at 70% lower concentration than using naked DNA alone.
Engineered exosomes were administered to the brain of transgenic reporter mice using the nasal route to test for intracellular protein delivery in vivo.
Haptens were conjugated to the keyhole limpet hemocyanin (KLH) carrier protein, and evaluated for efficacy against nicotine in mice using the clinically approved alum adjuvant.
As an injectable tissue engineering system of chondrocytes, very promising results were confirmed for nude mice, using the current polypeptide aqueous solution.
