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Figure 6 Comparison of mitochondrial ATP level between dying and surviving septic mice using prospective stratification of outcome.

Comparison of apoptosis in different organs between dying and surviving septic mice using prospective stratification of outcome.

Figure 4 Comparison of organ function between dying and surviving septic mice using prospective stratification of outcome.

Figure 5 Comparison of mitochondrial function between dying and surviving septic mice using prospective stratification of outcome.

Similarly, the TUNEL assay revealed only trivial changes: only isolated apoptotic cells in the lungs and liver of septic mice were observed (Additional file 2: Figure S2). Figure 7 Comparison of pathomorphologic changes mitochondrial function between dying and surviving septic mice using prospective stratification of outcome.

Further analysis is warranted using prospective datasets.

All mice used were males.

The mice used were 1 2 months old.

Table 1 Pathology score in organs Group Heart Kidney Lung Liver CLP-DIED 0 0.5 0.5 0.8 CLP-SUR 0 0.3 0.1 0.1 CONTROL 0 1.0 0 0.8 Scored organs were harvested from CLP-Only mice stratified using the prospective BT-based prediction of outcome and sacrificed on days 1 to 3 post-CLP.

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