Sentence examples for mice undergo progressive from inspiring English sources

These data clearly demonstrated that Ppt1-KI mice undergo progressive deterioration in motor coordination in an age-dependent manner.

Akita mice undergo progressive organ dysfunction in the kidney and retina after the onset of hyperglycaemia, exhibiting increased proteinuria, vascular permeability, increased apoptosis and alterations in the retina [ 21– 23].

PS1-KI mice undergo progressive impairment of spatial learning and memory at 9 11 m.o.a., while 3xTg-AD mice show age-dependent spatial memory decline developing as early as 5 6 m.o.a.o.a

Unlike the hindlimb muscles, the diaphragm of mdx mice undergoes progressive deterioration of muscle structure and function and is therefore a preferred muscle when examining the efficacy of potential therapeutic agents of clinical relevance [ 5- 7].

The articular cartilage of the knee joints of Mig-6-cko mice undergoes progressive osteoarthritis-like changes characterized by late-stage articular cartilage degradation, which is unexpectedly preceded by dramatic thickening of the articular cartilage.

In a study using relaxin gene-knockout (RLX-KO) mice, the RLX-KO mice underwent progressive increases in cardiac and renal collagen content compared with wild-type animals.

While the tumors in PBS-treated mice underwent progressive growth with average volumes reaching 368 mm by day 50, palpable tumors were only just evident in the ImmTAC-NYE-treated mice at this time point (Fig.  4c; p < 0.001).

These mice undergo a progressive decline in motor function resulting from the progressive loss of ADAR2-lacking AHCs over a period ranging from 2 3 months to 6 8 months of age (Hideyama et al, 2010); thus, if effective expression of the ADAR2 gene is achieved by AAV9-hADAR2 infection, motor dysfunction should be ameliorated through the prevention of the death of the AHCs.

Fixed LD 12 12 schedule runs is shown for 5 6 days, then all mice undergo a progressive reduction of the dark phase over 12 days.

In summary, we have shown that Lmna-/ mice undergo a progressive decline in the size of their thymus and spleen, a decline of developing B220+ B cells in the bone marrow, a decline of total developing thymocytes, and striking decreases in peripheral B and T cells.

With increasing age C57BL/6 mice undergo severe progressive sensorineural hearing loss (presbyacusis) starting around 4 5 months of age (Hunter and Willott 1987).