Sentence examples for mice to validate from inspiring English sources

We used ghrelin, GHSR and GOAT null mice to validate our antibodies.

In this study, Prnp−/− mice were immunized with AdhPrP in parallel with wt mice to validate the Ad vectors and immunization protocol in the absence of PrP tolerance.

We then carried reconstitution experiments by administering human recombinant MBL (rhMBL) protein to MBL-null mice to validate that the smaller infarct volume in these animals was attributable to the lack of MBL.

Recent studies have utilized cbx7-knockout mice to validate the tumor suppressor role of cbx7 in liver and lung carcinogenesis [ 2].

We are currently investigating signalling and proliferative capacities of T cells derived from homozygous FasLDeltaIntra mice to validate a co-stimulatory role of FasL reverse signalling.

In the present study, pharmacological and toxicological effects of this medicine was investigated in mice to validate the safety and efficacy of the herb.

For reference, we have shown the combined z-scores for the αCaMKII+/− mice used to validate the screen.

Our studies utilizing Epha3-null mice fail to validate a putative tumor suppressor function for EPHA3 in human lung cancer.

Mouse models of uremia are important tools for in vivo translational studies such as examining the impact of specific genes in transgenic or knockout mice and to validate potential therapeutic interventions prior to pre-clinical testing in humans.

Thus, EphA3-null mice fail to validate a putative tumor suppressor function for EPHA3 in human lung cancer, perhaps owing to functional redundancy between murine EphA receptors expressed in adult lungs.

Subsequently these putative enhancer sequences are tested in a transgenic mouse assay to validate their in vivo function and to determine their tissue specificity [ 17].