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To accomplish this, human periosteum derived cells (hPDCs) were seeded on hydroxyapatite/collagen scaffolds (calcium phosphate rich matrix or CPRM), or on decalcified scaffolds (calcium phosphate depleted matrix or CPDM), followed by subcutaneous implantation in nude mice to trigger ectopic bone formation.
To demonstrate wounding-induced activation of TG2 in vivo, the toll-like receptor 3 ligand, polyinosinic-polycytidylic acid (poly(I C)), was injected in mice to trigger small intestinal injury.
Diazepam has been used previously to increase the GABAergic tone in pre-critical period mice to trigger the onset of the critical period for OD plasticity and to block restored plasticity after reduction of inhibition in older rodents (Hensch et al. 1998; Fagiolini et al. 2004; Maya Vetencourt et al. 2008a; Morishita et al. 2010; Greifzu et al. 2014).
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Blue-light stimulation of DFI-ChR2 AAV infected striatal slices of these mice failed to trigger EPSCs at holding potentials of −70 or +40 mV (n = 6, Fig. 3C,D).
Mice expressing a version of E6 which lacks the C-terminal five amino acids that mediate binding to the PDZ domain render these mice unable to trigger unregulated cellular proliferation.
Inhalation or pharyngeal aspiration exposure of mice to SWCNTs triggers a robust inflammatory response whereby the initial sharp accumulation and activation of neutrophils is followed by the expedited recruitment and extended presence of macrophages in the lung.
From a mouse down event, to trigger a mouse up event, users replace the lifted finger on the touch surface, completing a click event.
It is interesting to note that MDM2 presentation in Agpos mice was sufficient to trigger TCR down-regulation, although previous studies suggested that effector CTL did not recognise normal tissues.
In stark contrast, doubling the gene dosage of the activated Ha-ras in homozygous Ha-ras transgenic mice was sufficient to trigger early-onset non-invasive urothelial carcinomas (Fig. 1) [ 46].
A single optrode made of a 50- μm multi-mode fiber was inserted in mouse brain slices to trigger localized epileptiform events in a single cortical site [ 18].
A sharpened 50- μm fiber coated with gold was inserted in mouse brain slices to trigger localized epileptiform events; the same optrode was later integrated into a recording silicon multi-electrode array, replacing the center electrode for optical excitation of cells in a single cortical site [ 35, 36].
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