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In this study we determine the ability of TLRs on pulmonary macrophages from old mice to recognize and respond to infection with the virulent pathogen Mycobacterium tuberculosis (M. tb).
Insel and colleagues have shown that oxytocin improves the ability of mice to recognize other mice (ScienceNOW, 3 July 2000), but he notes that this is the first time such a specific effect has been seen in humans.
In the study, published in the journal PLOS Biology, researchers from the University of Manchester were able to distinguish between the roles of light color and light intensity in the ability of mice to recognize the time of day.
CTL killing assays were performed to test the efficiency of activated T cells from infected spleens of transgenic mice to recognize and lyse target cells.
On the basis of these findings the occurrence of MHC-dependent olfactory cues was postulated that enable mice to recognize one another as individuals [2].
We first investigated the ability of the APP mice to recognize a previously met conspecific.
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Ultrathin cryosections were picked up in a mixture of 50% sucrose and 50% methylcellulose and incubated with primary antibodies (ATG16L1, ATG9 and rabbit anti-mouse to recognize TfR) followed by protein A gold (Utrecht).
The mice learn to recognize the tone and they freeze in fear when they hear it later, even without the shock.
Darcin-mediated learning of main olfactory odors is not the only way in which mice learn to recognize individuals.
It is well known that female mice learn to recognize their mate during a sensitive period around mating.
If this is the case, it is hardly surprising that DBA/2 mice fail to recognize food restriction as a signal for a starvation period.
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