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In this report we have used conditional gene targeting in mice to address the role of the deubiquitinating activity of CYLD in the myelomonocytic lineage.
We have generated and characterized OGR1-deficient mice to address several critical issues: 1) the physiological functions of OGR1 in mice; 2) the role of OGR1 in osteoclastogenesis; 3) the OGR1-dependent pH responsiveness using OGR1-deficient cells; and 4) the functions of OGR1 in other bone biological processes when mice are challenged by exogenous stimuli, such as tumor cells.
We have produced a panel of mutant FasL knock-in mice to address this question.
Serial dilutions of OTBCs were injected in nude mice to address their tumorigenic capabilities.
In this study, we utilized both female and male NZB/WF1 mice to address two fundamental questions.
We employed a genetic approach in mice to address the hypothesis that Shroom3 and PCP function together to coordinate CE with polarized bending of the neural plate.
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In this study, we have used the PLM3SA mouse to address this issue.
A better way is to use the mouse to address emails, but you need to have the addresses in your "Address book".
Therefore, we used tcl1tg mice as a CLL mouse model to address this question.
In this study, we have used MEFs from TG2 wild-type (Tgm2+/+) and TG2 deficient mice (Tgm2−/−) to address the potential role of TG2 during adipocyte differentiation.
Here, we used whole-body (WB) imaging techniques, including both standard magnetic resonance imaging (MRI) and diffusion-weighted WB imaging with background signal suppression (DWIBS) to follow-up the engraftment and systemic spread of human Ewing sarcoma xenografts in mice and to address the therapeutic efficacy of adoptive T-cell transfer against disseminated tumour cells in vivo.
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