Sentence examples for mice thus validating from inspiring English sources

Heard, for instance, used FISH probes positioned on either side of DXZ4 to visually demonstrate that chromosome folding differs on the active and inactive X chromosomes in mice, thus validating her Hi-C findings.

The inhibitory effect of c-Rel-siRNA on B lymphocyte proliferative responses as well as antigen-mediated immune responses essentially mimics the phenotype of the c-Rel knockout mice, thus validating the specific knockdown of c-Rel molecules by the siRNA.

Genes whose induction has been associated with the STAT3 signaling pathway were repressed in IL-6RαT-KO mice, thus validating the overall strategy for the analysis.

Ajeone was active against Plasmodium berghei in mice [46], thus validating the ethnobotanical use of the plant, meanwhile allicin was reported as a P. falciparum cysteine protease inhibitor [47].

Subsequently, they used PR3 to significantly reduce parasite load in P. berghei infected mice without host toxicity, thus validating the proteasome as a viable antimalarial-drug target [ 90].

Such an amount of chromatin would package roughly 2.3 Gbp of DNA which is only slightly lower than the sequenced mouse genome (2.5 Gbp) thus validating the estimated chromatin compaction.

Therefore, globally, the mouse receptor more closely reproduces the features of the human receptor, thus validating the mouse MCAo model utilized here as the most appropriate experimental model to assess the role of GPR17 in brain injury.

We have recently reported complete manifestation of TCRα LCR function in T cells derived in vitro from mouse embryonic stem cells (ESC), thus validating a complete cell culture model for the full range of LCR activities seen in transgenic mice.

However, enrichment analysis of an independent set of experimentally determined annotations, the MGI mouse phenotypes, highlighted the same biological processes, thus validating the GO results.

Compared to BALB/c mice, C57BL/6 mice are less susceptible to B. pseudomallei infection, regardless of the portal of entry, thus validating the model of differential susceptibility for various routes of infection (Table).

As expected, p53-pathway activity in mouse p53Δf tumors was completely negative (Fig 6D, p53 lane), thus validating the p53-pathway analysis.