Sentence examples for mice this led from inspiring English sources

In behaving mice, this led to spatially triggered episodes of network-wide hyperexcitability during exploration accompanied by the emergence of high-frequency discharges during rest.

In BDNF-knockout mice this led to reduced 5-HT metabolism [ 81] and aggressive impulsive behavior [ 82].

In direct comparison with lysates from Bcl-G −/− mice, this led to the identification of 19 proteins that were found to co-purify with both antibodies, but none of them belonged to the Bcl-2 family.

Osmotic pumps were used to obtain a 72 h continuous infusion of nigericin in mice; this led to dose-dependent killing of cells in KHT tumours with surviving fraction of approximately 0.1 at maximum tolerated doses.

In mice, this leads to degeneration of basal forebrain cholinergic neurons (BFCN).

Furthermore, testicular development is suppressed in bax −/− mice, but not in bax +/− mice, and this leads to the absence of androgen synthesis in the testes.

DNA damage accumulates in the intestine of aging G3 mTerc−/− mice, and this leads to impairments in the maintenance of ISPCs and an increasing atrophy of the intestinal epithelium in aging G3 mTerc−/− mice (Begus-Nahrmann et al, 2009; Sperka et al, 2011).

Combined with the recent work on IL-17 and Th17 cells in mice, this has led to an expanded understanding of the mechanism of host defense from C. albicans at mucosal surfaces and the role of IL-17 in immunity from infection.

Since the degree of inflammation will be different in different mice, this could lead to variability in the results within groups of animals exposed to the same antibody.

This is consistent with the observation of Santacruz and colleagues that inhibition of transgene expression in this mouse led to rescue of the memory impairment, but had no effect on the continued accumulation of abnormally phosphorylated or aggregated tau [ 12].

Although VFR did not have any effect on FBG of N mice, this surgical intervention led to a significant increase in FBG of df/df mice (P = 0.0020) (Fig. 1E).