Sentence examples for mice this effect from inspiring English sources

Interferon-γ-induced activation of ROS production by mitochondria in macrophages for the clearance of Listeria monocytogenes was also decreased in ERRα-null mice; this effect was again because of decreased expression of mitochondrial genes in KO mice53.

While we found a significantly higher number of sphere-forming cells in mammospheres from miR-34TKO mice compared to p53-null mice, this effect was restricted to the first passages (Fig. 3l and Supplementary Fig. 1c).

Although there is a secondary loss of rod function in Gnat2cpfl3/cpfl3 mice, this effect is modest and evident only in animals >9 months of age [20].

These results demonstrate that although JNK1 activity in myeloid cells contributes to an altered inflammatory profile and impaired insulin sensitivity in the adipose tissues of Jnk1−/− mice, this effect is rather modest in magnitude.

In the WT mice, this effect may be mediated by PPARγ ligands, either components or metabolites of the HFD, that have long term effects on the differentiation potential of BMSCs.

These results indicate that severe short-term CR in the young and old mice lowered lipid peroxidation potential, but in the senescent mice this effect was attenuated as a result of age.

While we observed some instances of increased rod-mediated ERG responses in treated eyes of the GC1KO mouse, this effect was not as consistent as that seen for cone responses upon treatment.

Loss of RORγ leads to an increase in total adipocyte numbers in female DIO mice and in ob/ ob mice, whereas this effect is less pronounced in male DIO mice.

Significant renal infiltration of T cells (CD3+) was seen at the end of week 5 in vehicle + ASLN mice compared to normal control mice and this effect was markedly inhibited in Citral + ASLN mice (Fig.  4a-c, g, h).

In line with this, the LXR agonist T09 was found to reduce the elevation in blood pressure due to chronic pressure volume overload in mice, whereas this effect was absent in mice lacking LXRα [ 75].

APP/PS1 mice that were injected with penicillinase showed a significant reduction in fear memory compared with wildtype penicillinase treated mice, and this effect was comparable to untreated mice.