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A blocking peptide was infused in three ApoE−/− mice; this condition served as another control.
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At five weeks of age, about one week after the onset of hyperglycemia, a decrease in MNCV was clearly present in Ins2Akita/+ mice and this condition was maintained (but it did not worsen) as mice aged (Fig. 1C).
To assess effect of PAF on the regulation of vasculature function during LPS-induced endotoxemia, we measured the mean arterial blood pressure (MABP) in mice with this condition.
Although this is not life-threatening, any mice developing this condition were culled to reduce discomfort and excluded from the survival study.
Under this condition, mice treated 13-1-e had no obvious detrimental phenotypes.
We have previously generated whole body Lrpprc knockout mice and demonstrated that this condition causes embryonic lethality (20), in agreement with results from an independent knockout strain (23).
Under this condition, mice treated with electro-acupuncture showed significantly reduced pain-related behaviour as withdrawal threshold was significantly higher and latency longer than control animals at the time of hypersensitivity development between 20 to 28 DPO.
Under this condition, mouse ESC (mESC) lines can be derived and subsequently propagated indefinitely.
Under this condition, mouse α-syn within neuronal processes in PBS-treated neurons was completely extracted, whereas neurons treated with pffs showed TX-100-insoluble aggregates.
Accordingly, in this condition, B1B2KO mice also showed higher glucose tolerance after glucose stimulation.
This condition in mice mimics many of the clinical and pathological features of human RA.
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