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Given that the objective of our study was to compare the magnitude and dynamics of organ injury/dysfunction in early murine sepsis between acutely dying and long-term surviving mice, the time of septic death was a critical endpoint.
Based on either calliper or volume by imaging measurements, tumour growth was abolished (despite inter-animal variability) in all rituximab-treated animals, while in vehicle-treated mice the time to double the tumour volume was 6 days, as analysed by their exponential growth rate.
In BL/6N mice, the time spent in the lit compartment was not affected by 4 weeks of CMS pre-experience (Figure 2C).
In NG2 null mice, the time for 50% incidence was extended to 80 days.
In these mice, the time to tumor recurrence and long-term survival were monitored over the next 100 days.
In the transplanted mice, the time to disease onset is shortened from 1 year to about 3 months, which vastly facilitates analysis (Hofbauer JP, Egle A, unpublished [ 26]).
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For each mouse, the time spent with each of the three containers was divided by the total time spent investigating the containers to arrive at a percent time with each choice of bedding.
In 18L 6D FAA reappears in some mice at the time of previous entrainment to food availability when Bmal1−/− mice are food deprived.
Compared with sham-operated mice, SBP was increased dramatically in Lacz-infected DOCA-salt-treated mice during the time course.
Tfr2−/− mice have a greater amount of bioavailable iron for invading schistosomes than wild-type mice at the time of infection.
Lara-González and colleagues [22] discovered that the administration of AgNPs to tumor-bearing mice at the time of tumor injection caused significantly increased survival, compared with controls.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com