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In Dicer1-hypomorphic mice, the size of the pancreas in adults (8 10 weeks of age) was nearly identical to that in the wild-type mice; however, there were more small islets (Fig. 4).
In hippocampal cultures from APPPS1-21 mice, the size of the readily releasable synaptic vesicle pool was decreased, while in a single-mutant APP transgenic model (APP23, APPswe), this effect was not observed (Priller, 2009).
In adult knock-out mice, the size and appearance of BAT is similar to the wild-type animals [26].
After the cells were inoculated subcutaneously into nude mice, the size of the tumour was measured twice a week.
In nude mice, the size of tumours arising from SiHa cells was reduced by 87%, in contrast to no reduction in tumour size arising from HeLa cells.
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In Snord116del mice, the sizes of testes and ovaries were proportional to their body size and histologically normal.
Although round inclusion bodies were observed in AVP neurons of the SON in both ad libitum and WD groups in 3-month-old FNDI mice, the sizes were smaller in the mice subjected to WD for 4 weeks.
Although T-antigen expression was able to induce beta-cell proliferation and reverse diabetes in the Perk KO mouse, the size of their insulinomas were on average 38-fold smaller than seen in wild-type littermates (Figure 3).
In mouse, the size of IFN-α subtypes is variable.
Thus for the mouse, the size range was a reliable predictor of true full-length proteins.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com