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Exact(5)
Indeed, in spite of the greater APP expression in the transgenic mice the initial turnover of APP is similar in Tg2576 and wild-type mice, although a greater proportion of APP stably persists following extended cycloheximide treatment in the APP overexpressing transgenics.
In mice, where Dicer has been conditionally deleted using the Chx10Cre transgenic line ("CKO" mice), the initial retinal lamination during development was normal [27] but the authors detected retinal degeneration phenotypes, including the formation of photoreceptor rosettes, at more mature ages starting at P16 [27].
These conflicting reports in the literature may be due to differences in the ages of mice, the initial dose of infecting bacteria and/or the microbial flora/status of mice in different laboratories.
Now identified in both rodents and humans, in mice the initial polarization of naive Th cells towards the Th17 subtype depends on T-cell receptor signalling and the presence of transforming growth factor (TGF -β and IL-6 [ 3, 4].
For example, in mice, the initial marked slowing of paracetamol absorption induced by acute administration of liraglutide diminishes within 2 weeks of continuous dosing, whereas the initially comparable marked slowing of paracetamol absorption induced by exenatide is sustained (68).
Similar(55)
Accordingly, there were no systematic differences in performance between control mice, Tau mice, and Swede mice in the initial olfactory tasks performed at six months of age.
Similar to overall performance, there were no systematic differences in block 1 performance, and thus in speed of olfactory learning, between control mice, Tau mice, and Swede mice in the initial olfactory tasks performed at six months of age.
Although we cannot exclude the possibility that Raldh2 is weakly expressed in forelimb LPM and it was not detected, in mouse, the initial source of RA may be neighboring paraxial mesoderm tissues such as the somites that are known to produce RA.
Escalating concentrations of S100A6 were also observed in sera collected serially at 1, 2, and 4 weeks p.i. from individual mice within the initial cohort of 20 mice given the parental SKOV-3 cell line (data not shown).
In both groups of mice, after the initial changes at the start of the exercise period, the average RER remained fairly constant and did not differ between groups (0.925±0.029 and 0.924±0.034, in Myog-deleted and wild-type, mice respectively).
The preference for the outer zone of the MWM observed in these trials in all groups of mice reflects the initial response to the MWM that was also present in the first training trial of the first MWM session (Figure S1B).
Related(20)
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mice the nuclear
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