While IL-33 is highly expressed by the RPE cells in the naïve BALB/c mice, the expression level was low in these cells in the naïve C57BL/6 background mice.
When the Il19 gene is inactivated in mice, the expression level of pro-inflammatory cytokines increases [12].
After grafting to athymic mice, the expression patterns suggest a normalization of cultured skin substitutes to a phenotype more closely resembling uninjured human skin.
To clarify the possible mechanism of the effects of carbon dots to the immune system in mice, the expression levels of IL-12, IFN-γ, IL-4, and TNF-α in the spleens of mice treated with carbon dots were detected by Western blot.
In these mice, the expression of the LacZ product X-Gal depends on GATA3 promoter activity.
In our Cre transgenic mice, the expression of Cre was exclusively observed in most parts of the hippocampus.
In heterozygous gata3 null mice the expression of gata3 correlated with high levels of activated Akt/PKB.
In the pancreas of our Dicer1-hypomorphic mice, the expression levels of miRNA changed slightly compared to wild-type level which is why the mice could survive.
In these mice, the expression of the H-Y TCR was dependent on the machinery that normally directs V(D J recombination of the endogenous TCRα locus.
In the Tex19.1 mutant mice, the expression of rtTA and LacZ is expected to be under the control of the endogenous Tex19.1 promoter.
In comparison to WT mice the expression of both the 38 kD and 34 kD mFasL bands were significantly increased in ΔCS mice (Figure 2B and 2C).
