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In the obese mice, the activity of an interacting set of genes was turned down.
Figure 7 showed that L-arginine could decrease significantly the activity of pepsin in FD group (p < 0.01) compared with normal mice; the activity of pepsin was increased (p < 0.05) in administration group compared with FD group after i.v. with oMWCNTs of 500 μg/per mouse, but still lower much than normal level (p < 0.01).
In HFD-fed mice, the activity of complex II was significantly reduced to 46.7±11.1% (P<0.001) of control activity.
In MuRF1 KO mice, the activity of 4 of these subunits and overall β5 activity was higher in the KO mice than the WT.
In HFD-fed mice, the activity of complex III was reduced to 54.1±8.1% (P<0.001) of control values (Fig. 3A), but treatment of HFD-fed mice with MLT, MnTBAP or uric acid avoided this decrease.
In 2011, Otte and colleagues discovered that in G72 transgenic mice the activity of complex I in the respiratory chain was attenuated, presumably through the binding between the flavin-mononucleotide (FMN) group and pLG72 [ 19].
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In the liver homogenates of Cyp-treated mice, the activities of SOD, CAT, GST and the level of GSH decreased significantly, while the level of LPO increased significantly.
In WT mice, the activities of all 20S and 26S catalytic subunits, except for the 26S β2, significantly decreased with age, accounting for the observed accumulation of polyubiquitinated proteins.
In Drosophila and in mouse the activity of Trx-G/MLL complexes is required to prevent Pc-G-mediated silencing of transcribed Hox genes [31], [32], [33], [34].
For each mouse, the activity of tissue samples was calibrated against a pre-measured aliquot of the radiotracer and normalized to the whole bodyweight and to the residual radioactivity present in the tail.
Germ-free mice still have the same amount of growth hormone as other mice, but the activity of IGF-1 in their blood, liver, and muscles is lower, Leulier's team found.
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