Sentence examples for mice that spontaneously develop from inspiring English sources

Because sustained immune activation and hyperexpression of COX-2 and c-FLIP contribute to lupus, we treated SNF1 mice that spontaneously develop human lupus-like disease with apigenin.

Also, everolimus, a TOR inhibitor, markedly delayed tumor development in transgenic mice that spontaneously develop ovarian carcinomas [ 46].

DHA-dFdC significantly extended the survival of genetically engineered mice that spontaneously develop pancreatic ductal adenocarcinoma.

Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus.

We investigated whether an ENO1 DNA vaccine elicits antitumor immune responses and prolongs survival of mice that spontaneously develop autochthonous, lethal pancreatic carcinomas.

In order to further analyse the role of PAI-1 in tumor growth and metastatic dissemination, we used transgenic PyMT mice that spontaneously develop mammary tumors.

Several years ago, Benoist et al. described in Cell a T-cell transgenic mouse that spontaneously developed severe arthritis (KRN model).

Briefly, alopecic skin from a C3H/HeJ mouse that spontaneously developed hair loss was grafted onto 8 10 week old C3H/HeJ mice free of disease.

Adipue and colleagues [ 1] describe a new strain of mouse that spontaneously develops a chronic inflammatory, possibly autoimmune, arthritis that shares many similarities with human RA and other mouse models of arthritis.

We test whether oxidative stress induced by IOP elevation triggers DRP1 and DRP1 S616 phosphorylation-mediated mt fission in the RGC and probe for degeneration in its axon using the glaucomatous DBA/2J (D2) mouse that spontaneously develops elevated IOP.

The present study addressed whether the K-Ras 4A proto-oncoprotein can suppress tumour development in the absence of its oncogenic allele, utilising the ApcMin/+ (Min) mouse that spontaneously develops intestinal tumours that do not harbour K- ras activating mutations, and the K- rastmΔ4A/tmΔ4A mouse that can express the K- ras 4B splice variant only.