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The presence of these vesicles has also been observed in other mutant mice that include tulp1 [47], [47], tubby [48] and pcd [49].

Arginine supplementation by DMD patients stems from reports that short-term, arginine treatment for 2 6 weeks has beneficial effects in young, mdx mice that include increased utrophin expression, increased force production, decreased inflammation and decreased fiber damage [31] [34].

In summary, we have shown that GPRC6A has multiple functions as evidenced by abnormalities in GPRC6A null mice that include alterations in circulating testosterone and estrogen levels and feminization of male mice, defects of bone density and bone cell function and abnormalities in the renal handling of calcium and phosphate, hyperglycemia and liver steatosis.

We and others have characterized a series of morphological and phenotypical alterations in NHERF1-deficient mice that include phosphate reabsorption impairment, altered intestinal brush border membrane, lack of development of the lobuloalveolar lactating mammary gland and abnormalities of cochlear cilia bundles with hearing defects [ 15, 16, 18, 19].

The intermediate classes often lie in between (see Figure 8 for results from three mice that include parametric changes in drop and air-blow intensities, Data from Mouse#1 is presented in A and B; Mouse#2 in C and D, and Mouse#3 in E and F, respectively).

Similar(55)

DDTs are noted for their relatively high dose effects, causing a tremor syndrome in adult mice that includes hyperactivity, ataxia, and paralysis (Herr et al. 1985).

Isolated ventricular mouse myocytes and the mediastinal area of anaesthetized mice (that included the heart) were exposed to graded doses of irradiation (sham 4 and 20 Gy) and investigated acutely (after ~1 h) as well as chronically (after ~1 week).

To confirm the higher tumorigenic potential of hCSCs in vivo, we carried out a xenotransplant experiment in NOD-SCID immunodeficient mice that included four treatment groups and a negative/naive control group.

Cluster 1 is functionally enriched in "lung" and "vascular" development, with corresponding mouse phenotypes that include "abnormal vascular development, alveolar morphology and respiratory mechanics".

These mice produce offspring that include XX and XY males (mice that have Sry and develop testes) and XX and XY− females (mice that lack Sry and develop ovaries).

To analyze MSCV promoter activity without the influence of the variability we observed among the individual manual injections, we transduced the lentiviral vectors into B6D2F1 mouse embryos and generated 8 transgenic mouse lines that included lentiviral vector provirus genomes in their chromosomes.

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