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In August, Ilseung Cho, of the New York University School of Medicine, published a study showing that antibiotics eradicated bacteria, commonly found in the digestive system of mice, that help the animals metabolize calories efficiently; without the microbes, the mice absorbed more calories from the same amount of food and rapidly became obese.
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In a big step toward understanding how genetics confers immunity to tuberculosis, researchers have identified a gene in mice that helps them restrain the bacterium behind the disease.
Yin Li, a senior at Stuyvesant High School in Manhattan, won in the individual category for research on nerve cell activity in mice that could help improve understanding of human brain function.
Much has been learned from gene "knock out" mouse models that helped to identify major synaptic regulators.
We present a new double reporter mouse line that helped to characterize the activity pattern of miR-9 in different cell types in the brain.
James takes the genes that help mice fend off human malaria and transfers them into mosquitoes.
Yang, Flynn et al. uncovered that the mutations in WDR5 that abolish lncRNA binding also affect the expression of genes that help mouse stem cells to maintain this potential.
Comparing the DNA of the original mice with their offspring, the biologists pinpointed four regions of genetic code that help tell the mice what kind of burrow to construct.
To translate our in vitro and in vivo diagnostic strategies we will utilize mouse models of human cancer that help us to test our approaches prior to clinical translation.
The method speeds up the development of "knockout" mice that lack a particular enhancer, helping reveal its function.
For scientists studying HIV drugs and vaccines, "it would be an enormous technical advantage" if this information could help create laboratory mice that can sustain HIV infection, he says.
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