Sentence examples for mice that generate from inspiring English sources

And while other companies have mice that generate human antibodies too, "our mice make more diverse antibodies".

We have investigated the effect of the antiangiogenic protein HRG on orthotopic PDGF-B induced glioma development in vivo using the Ntv-a Arf-/ mice that generate a high proportion of malignant tumors.

BACE1 knockout (KO) mice that generate low levels of Aβ and BACE1- and BACE2-deficient double KO mice, which do not express Aβ, have mortality rates of 40 and 60 percent, respectively.

In addition, mouse apoE appears to be more prone to lead to parenchymal plaque formation while human apoE4 is more prone to lead to CAA formation in mice that generate wild type human Aβ peptide [ 10, 24].

The American Association for Cancer Research consensus conference workshop broadly defined a cancer stem cell as "a cell within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor [ 2]." Single cells in mice that generate tumors represent the gold standard for cancer stem cells.

These mice generated a Th1/Th17 response in leukocytes and pulmonary lymph nodes against cryptococcal infection, in comparison to wild type mice that generated a Th2 profile.

The AQP4 null mice that generated a robust T cell reaction against the second extracellular loop of AQP4, loop C, did not develop autoimmune neurological disease as they do not express the target antigen.

A mouse with a brain made entirely of human cells would probably discomfort many people, as would a mouse that generated human sperm or eggs.

Dr. Weissman said undesirable outcomes like a mouse with a brain made of human cells or a mouse that generated human sperm could be avoided by deleting certain genes from the human cells before injecting them into a mouse.

Transgenic mouse models that generate spontaneous mammary tumors have been developed using promoters such as the mouse mammary tumor virus (MMTV) promoter to drive oncogenes, including polyoma middle T antigen (MMTV-PyMT) and ErbB2/Neu (MMTV-Neu) (for review see [ 5]).

Interestingly, there has been extensive neurotoxicity described in mouse models that generate pyroglutamate-modified Aβ [ 74, 75].