Manipulations used to modify DISC expression include the use of transgenic mice that express various forms of DISC1.
Wnt4 expression was activated during chondrogenesis using Col2a1-Cre transgenic mice that express Cre recombinase in differentiating chondrocytes.
The investigators gave injections of minocycline to 6-week old mice that expressed the symptoms of HD.
Gurney, M. E. et al. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
They then crossed the founder mouse with mice that expressed the Cas9 protein, producing zygotes whose hgRNA sequences started being cut and mutated shortly after fertilization.
We crossed these animals with the ROSA26tm14 CAG-tdTomato ROSA26tm14 CAG-tdTomatoreporteromice prothat undexpressmodified Rosa26 locus (hereaftdTomatoed the Ai14(tdTomato) mice)23.
This has become possible with a specific transgenic mice that express light-gated ion channel, channelrhodopsin-2, in olfactory receptor neurons.
Here, we report the generation and characterization of transgenic mice that express the catalytic subunit of telomerase (mTERT) at high levels in a broad variety of tissues.
Transgenic mice that express a truncated, constitutively active form of the sterol-regulatory-element-binding protein 1C (SREBP1C) transcription factor under the control of the adipose-specific aP2 promoter.
Mutant mice that express low levels of BubR1 protein develop progressive aneuploidy but form tumors only after being challenged with a carcinogen12.
Infertility was induced by G4-mZP3 in three strains of mice that express Ly49H, on two different histocompatibility-2 (H-2) backgrounds.
