Sentence examples for mice that enable from inspiring English sources
Using Fucci reporter mice that enable in vivo visualization of cell-cycle status, we detect increased proliferation during pre-HSC expansion followed by a slowing down of cycling once cells start to acquire a definitive HSC state, similar to fetal liver HSCs.
To overcome these problems, the investigators generated conditional Brca1 knockout mice that enable tissue-specific inactivation of BRCA1 by Cre recombinase-mediated deletion of one or more Brca1 exons flanked by loxP recombination sites (Jonkers and Berns, 2002).
CellEase-based protein release was demonstrated in vivo using capsules implanted intraperitoneally into mice that enabled the doxycycline-controlled release of a model glycoprotein and accumulation in the bloodstream of treated animals.
Here we generated an E-cadherin-GFP mouse that enables intravital photobleaching and quantification of E-cadherin mobility in live tissue without affecting normal biology.
By identifying key tissues through serial microPET imaging, ROIs were established in each mouse that enabled the quantification of tissue concentration as a function of time.
A new transgenic mouse that enables tissue-specific GFP labeling of cilia creates new opportunities for using live imaging to understand cilium function and to better characterize the many genetic models of ciliopathies.
Since then one of the most important advances in HD research has been the generation of various mouse models that enable the exploration of early pathological, molecular and cellular abnormalities produced by the mutation.
In summary, due to a lack of mouse models that enable strict lineage targeting in the haematopoietic stem (HS /PC population, it has not been comprehensively determined previously whether these cells can serve as targets for transformation in MM.
He also branched out a bit and learned about the brain structures that enable mice to "sing" in ultrasonic ranges beyond human hearing.
Since endothelial-specific deletion of FAK induces lethality during mouse embryonic development (Braren et al, 2006; Cohen & Guan, 2005; Ilic et al, 1995), we have generated a new mouse model that enables us to induce endothelial FAK deletion in adult mice upon tamoxifen treatment.
We used a transgenic mouse system that enabled isolation of small numbers of Oct4ΔPE GFP-positive germ cells in vivOct4ΔPE GFP-positiveferentiation from mESCs in vitro, to uncover quantitate and qualitative phenotypes associated with the disruption of a singermtranslational regulator, Dazl.
