In vivo, in mice suffering from glomerulonephritis, E-selectin-retargeted adenovirus selectively homed in the kidney to microvascular glomerular endothelium.
To test this thought he and his colleagues treated mice suffering from Myc-driven myeloma with JQ1.
Furthermore, compounds 3f, 3p, 3r were subjected to KM mice suffering from S-180 carcinoma subcutaneously, which possessed more potent than Fluorouracil, a typical anticancer drug used clinically.
Favorable results with a silymarin formulation were reported in mice suffering from a streptozotocin plus high-fat diet induced NASH.
The researchers tested the approach on mice suffering from blood clots.
One of his early experiments showed the diversity of bacteria living in the gut was greatly diminished in mice suffering from early life stress.
Marazzi and colleagues found that captothecin protected mice suffering from these dual infections, saving 94% of them, whereas all of the untreated mice perished.
A study published in tomorrow's Proceedings of the American Academy of Sciences describes how modified buckyballs--which soak up nerve-destroying chemicals--delay the onset of symptoms in mice suffering from Lou Gehrig's disease.
When Ghadari and his co-workers injected peptides selected for potency against the pathogen Staphylococcus aureus into mice suffering from a bad infection with that bug, 100% of them survived for the entire 1-week trial.
Researchers at Harvard and Columbia found that in mice suffering from something akin to amyotrophic lateral sclerosis (Lou Gehrig's disease), astrocytes secrete a toxin that kills muscle-controlling neurons.
The data outlined here demonstrate that both the expression of VH and V kappa gene families and their association is skewed in mev/mev mice, suffering from systemic autoimmune disease, and differs significantly from phenotypically normal mev/+ litter mates as well as the C57BL/6 background strain.
