"What inspired him to take on this challenge was his research on how hormones control critical ovarian functions in mice, such as oocyte maturation and ovulation.
New outlook: A technique called Raman spectroscopy can image nanoparticles within the bodies of living mice, such as in the liver (shown here).
Every employer is obliged to provide employees with a desk assessment or training on how to set up their workstations to suit individual needs, and many make available ergonomic keyboards and mice (such as the one Smith uses).
The most used models are xenografts of human tumors grown subcutaneously in immunodeficient mice such as athymic (nude) or severe combined immune deficient (SCID) mice.
Infection triggered similar cytokine storms in both genotypes as illustrated by the equivalent large quantities found in the bloodstream of Ripk1LPC-KO and Ripk1fl/fl mice, such as for TNF-α, IL-6, and CCL2 (Fig. 1b).
Obese mice, such as ob/ob and db/db mice, and long-term high-fat-diet (HFD) fed mice, are usually used to investigate the mechanisms of hepatic TG homeostasis.
Fourier transform infrared spectroscopy spectra reflect the alterations on major biochemical constituents in brain tissues of mice such as proteins, lipids and nucleic acids due to the overproduction of ROS.
The use of microdialysis in mice for pharmacokinetic and drug delivery studies owes much to the recent availability of genetically engineered mice, such as mice in which the genes encoding multiple drug resistance have been knocked out.
In this chapter, the types of genetically engineered mice, such as transgenic, knockout conditional knockout, and knockin animals, and the general techniques on how to obtain them are described.
Traditional approaches such as the sucrose/saccharin-substitution procedure that normally accentuate ethanol drinking in rodents have had limited success in low drinking/preferring mice such as the D2 line.
The most likely explanation for this negative finding is the potential developmental upregulation of non-P2X7 P2X receptors in P2X7-/ mice, such as P2X3 or P2X4.
