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Exact(7)
Despite plasma thymidine concentrations being higher in rodents as compared to humans [8], the lack of a simple relationship between plasma or tumour thymidine concentration and [18F]FLT uptake in the mice studied here suggests that this may also be the case in patients.
In that paradigm, ligand KO mice had a higher rate of arrests than observed for DKO mice studied here in their home cages.
It therefore seems unlikely that the loss of flash ERG responses at all but the highest stimulus intensities in the relatively young Gnat1−/− Gnat2cpfl3/cpfl3 mice studied here is a consequence of generalized rod dysfunction.
The WT control mice and the TSP-2-null mice studied here have been described previously [ 4].
In the mice studied here, the 2-month-old Brtl/+ mice have completed their tooth development and have been weaned for about a month.
The adult mice studied here showed an approximate 30% lower gastrocnemius muscle mass compared with age-matched WT mice (Table 1).
Similar(53)
The trNK cells in the uterus in virgin mice as studied here will also need to be studied with respect to other subsets of uNK cells which have been described previously, including endometrial vs decidual NK cells, and NK1.1– DX5– uterine NK cells (Yadi et al., 2008; Mallidi et al., 2009).
It is of course possible that the expression of this putative additional NMU receptor is upregulated in the mice we studied here, as a physiologic compensatory mechanism for the absence of the known NMU receptors, and that its contribution to the pro-inflammatory activities of NMU is therefore apparent only in the absence of the known NMU receptors.
In the mouse models studied here, we found that the majority of bacilli were indeed intracellular within macrophages through most of the infection.
The LmnaDhe mouse model studied here exhibits physiological phenotypes similar to human progeria and related laminopathies characterized by lipodystrophy, cranial abnormalities, and skin defects [29].
Analysis of Xenopus embryos suggests a mechanism for the homophilic cell sorting observed in the female conditional Efnb1 mutant mouse embryos studied here [Lee et al., 2008].
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