Sentence examples for mice so as from inspiring English sources

The purpose of this work was to study the biodistribution pattern of the fifth generation of poly(propylene imine) dendrimer (PPI-5.0G -based PPI-5.0G -basedannose and lactose)-coated glycodendrimers in mice so as to exPPI-5.0G -basedtial of these systems as drug carbohydrate

All the experiments described in this study were intentionally performed using different strains of mice so as to exploit and compare the unique genetics and phenotypes of their ovaries and oocytes with the ultimate aim of reconciling one model for mechanism(s) of DNA repair and its relation to oocyte loss.

Many scientists agree that the most powerful technologies for determining gene function involve genetic manipulations that knock out, replace, or overexpress gene products in mice so as to evaluate functional consequences.

To study the effects of this modified Ang-1 in experimental models of sepsis, Alfieri and colleagues implanted window chambers into the dorsal skinfolds of mice, so as to visualize skeletal muscle blood flow with laser Doppler imaging.

In this study, we investigated the effects of vismodegib, given orally to mice so as to mimic how it is administered to patients, in order to provide a potential explanation for the distortion in taste perception that is reported to occur in up to 55% of patients taking vismodegib for BCC.

This suggests that it may be prudent to create more suitable animal models besides mouse so as to verify MSC-mediated immunosuppression in vivo.

We are trying to generate a UXT conditional knockout mouse, so as to address whether UXT could modulate angiogenesis in mammals and, if so, whether UXT could attenuate Notch signaling in mice.

The distribution of Jaccard indices for all possible pairs of mice is shown in Figure 2. We carried out these analyses both by using the complete sequence sets for each mouse, and also by subsampling equal numbers of sequences from each mouse, so as to avoid any bias imposed by sample size.

To investigate whether abnormal TH levels would lead to hepatic features similar to NAFLD, we treated mice with methimazole (MMI) so as to render them hypothyroidism (hypothyroid mice) (Additional file 1: Figure S1) [ 18].

Mice were chosen in accordance with the recommendations of the Mouse Phenome Database (MPD) so as to cover as much genetic diversity as possible [15], the density of genotypic information available in each strain and their suitability with the experimental design.

Eight weeks later, manifest mice were treated with tamoxifen so as to "switch off" the expression of human α-synuclein in dopamine neurons, and were then randomly assigned to receive either daily injections of CsA or vehicle solution.