Although wild type developed severe AHR, CD81 mice showed normal airway reactivity and reduced airway inflammation.
When tumor size exceeded 8% of body weight, GHRH-treated mice showed normal urea, creatinine, and kidney volume, while controls displayed signs of renal insufficiency.
The NOD mice showed normal blood glucose levels for 80 100 days [40].
As shown in Fig. 4, cisplatin administration resulted in renal tissue damage including tubular necrosis, dilatation, and hyaline cast, whereas the control and the control + DMTU mice showed normal renal morphology.
Furthermore, BMDMs from Irf8-null mice showed normal expression and induction of Arg1 mRNA (Fig. 5C) and protein (Fig. 5D) following IL-4 stimulation, confirming that IRF8 is dispensable for IL-4-induced expression of Arg1 in macrophages.
ILS mice showed normal hearing thresholds at twelve weeks of age.
Wild-type mice showed normal retina at all ages examined (Fig. 2A).
Germ-free AOM-treated Il10−/− mice showed normal colon histology and were devoid of tumors.
In this analysis, DGKβ KO mice showed normal cortical laminar structure (Figures 6a d).
Further flow cytometry analysis revealed that ADAM8 deficient mice showed normal development and expansion of immature thymocyte subsets.
In contrast, doubly mutant mice showed normal levels of IL1ß mRNAs and normal or slightly increased levels of MIP1α mRNAs.
