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Both mdx and ms-DKO mice showed dramatic elevations in βcyto-actin expression in skeletal muscle extracts when compared to wt (13.8±1.4 and 8.1±0.9 fold respectively) (Fig. 1 B).
Skin sections from avicin-treated mice showed dramatic decrease in the levels of VEGF accompanied by a decrease in CD31 staining, which is indicative of a reduction in angiogenesis.
Because irradiated Fus1 KO mice showed dramatic decrease in crypt regeneration, we compared the effect of PM on crypt regeneration in WT and Fus1 KO mice.
Interestingly, ApcΔ 716 op/ op compound mice showed dramatic suppression of intestinal polyposis, and macrophages were not found in the polyp tissues.
In contrast to a modest effect of O3CB in B6 mice, C3 mice showed dramatic changes in SDNN and rMSSD responses, indicating that HR regulation was uniquely different between strains.
Nevertheless, individual chimeric mice showed dramatic differences in terms of growth or rejection of s.c. injected B16 melanoma cells of C57 origin, which was clearly correlated with the level of skin chimerism (Table 1).
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Park, D.S. et al. Caveolin-1 null mice show dramatic reductions in life span.
At first view, our data seems to be inconsistent with the observation that CD152−/− mice show dramatic lymphocyte infiltration of tissues [14], [28], [35], [47].
The progeriod ZEMPSTE24-/ mouse shows dramatic alterations in heterochromatin architecture, accompanied by increased DNA damage, by the activation of the authophagic response and by downregulation of the mTOR pathway [ 32, 56].
However, recently Chicago-area white-footed mice also showed dramatic changes in morphology and mtDNA haplotype frequencies when invading urban environments [10] [11].
The db/ db mice also showed dramatic glycosuria, with glucose levels of 7,580±1,009 mg/dL, compared to 78±6 for wild type.
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