Mice that had received peptide vaccination but not unvaccinated or sensitized mice showed specific splenocyte proliferative responses to the carrier protein KLH (Fig. 5c, P+/S−, P+/S+).
Western blot analysis of spinal cord samples from WT and KO mice showed specific expression of membralin in the ER but not in the cytosol or mitochondria.
We found that c-rel−/− mice showed specific immunoreactivity for α-synuclein with the degeneration of dopaminergic neurons in the substantia nigra pars compacta.
Like 39,XO mice, COUMATE-treated mice showed specific impairments in accuracy at short stimulus durations on the 5-CSRTT, and, as in 39,XO mice, these drug-induced deficits were rescued in the less attentionally demanding 1-CSRTT.
MGP analysis on signal pathways revealed prominent changes in toll-like receptor (TLR)- and type 1 interferon (IFN -signaling IFN -signalingF and SPF mine, but not 5WexGF mice, whiLI 5WexGF mice shofed specific changes in chemokine signaling.
Double immunofluorescence studies on sciatic nerve sections from MAG 1-3 -Fc treated MAG 1-3 -Fc specific immunostreated for humiceFc γ chain reshoweded to axonspecificncimmunostaining axonal receptor(s) (data not shown).
At 15 weeks of age sera from vaccinated rCD34 mice showed specific anti-HER-2 IgG antibodies, based on their ability to immunoprecipitate HER-2 from a SK-OV-3 cell lysate.
Studies in the developing mouse heart show specific Pcan modifications (i.e., sulfations) are required for binding of different FGF-FGFR complexes (Allen and Rapraeger 2003).
In contrast to the liver-enriched transcription factors HNF1α, HNF3α, HNF6, and CAAT/enhancer-binding protein (C/EBP α, which when disrupted in the mouse genome the mice are viable but show specific effects on hepatocyte differentiation, metabolic function, and gene expression [ 3- 6], disruption of the mouse HNF4a gene is embryonic lethal [ 7].
