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In contrast, liver-specific HDAC3-knockout mice show significant lipid accumulation resulting from increased triglycerides (TG) and overexpression of peroxisome proliferator-activated receptor gamma (PPARγ) genes (Knutson et al., 2008).
The α-Nrx KO mice show significant impairments in Ca2+-triggered Ca2+-triggereder release at both excitatory aneurotransmitternapses, possibly due to effects on the preleaseptic orgatization of voltage-gated Ca2+ channels (Missler et al., 2003).
Furthermore, ecSOD−/− mice show significant reduction of H2O2 levels in both non-ischemic and ischemic hindlimbs.
Orexin KO mice show significant hypoactivity compared to their WT littermates for high activity behaviors (P<0.001, Mann-Whitney) (Fig. 2C).
Our recent analysis of skeletal muscle revealed that TWEAK-Tg mice show significant muscle fiber atrophy at the age of 4 6 months (Mittal et al (2009), unpublished observation).
The ABIN1[D485N] knockin mice show significant expansion of myeloid cells in various organs [ 14].
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Thirteen-month-old mice showed significant recovery within 7 days of treatment.
Comparing to vitamin C-treated mice, CMZ-inoculated mice showed significant decreases in relative weights of the spleen and thymus.
The dynamic PET ratio curves are given in Figure 4, where tg and ctl mice showed significant differences in PET.
After immunization, mice showed significant MHC-II mediated immune responses and their antisera recognized human MCF-7 breast cancer cells.
Female mice showed significant changes in the light dark box at both doses, but no significant changes in open field behaviours.
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