Sentence examples for mice show severe from inspiring English sources
Taurine transporter knockout mice show severe retinal degeneration at an early age.
BAG3 null mutation mice show severe striated muscle degeneration and early lethality, characterized by myofibrillar myopathy [16].
The mutant mice show severe segmentation defects in the cervical, thoracic and lumbar area with fused vertebrae and fewer ribs (Figure 5F 5H; Table 3).
At ≥9 months of age, 5XFAD mice show severe memory deficits together with further developed Aβ pathology and marked synaptic degeneration and neuronal loss [9], [21], [28], [30], [31].
Jag2 is expressed in the AER from E10.5, and its mutant mice show severe syndactylism that is equivalent to the phenotypes of Notch1&2DKO and presenilin1&2DKO mice, suggesting the exclusive role of Jag2 in this process.
Similar complications may underlie the fact that the overexpression of NMDA receptor 2B enhances hippocampal LTP and learning [67], whereas PSD-95 mutant mice show severe impairments in spatial learning and SAP102 mutant mice have mild impairments despite of enhanced hippocampal LTP [48], [49].
Several studies demonstrated that adiponectin knockout (APN-KO) mice showed severe injuries during cerebral ischemia-reperfusion [ 205, 206], while adiponectin injected APN-KO mice were reduced pathological ischemia-induced damage [ 207].
PGRN has protective functions in atherosclerosis, as PGRN and ApoE double KO mice showed severe atherosclerotic lesions compared with ApoE KO mice.
In contrast, the histology of untreated mice showed severe inflammatory reactions such as infiltration of inflammatory cells, alveolar collapse, alveolar hemorrhage and bronchioli terminals epithelium damage (Fig. 5b).
Mdx mice showed severe sarcolemmal fragility marked by Evans blue dye accumulation in numerous muscle fibers.
Excisional (6 mm) wounds created on the back of these mice showed severe impairment in closure when compared to their corresponding control (heterozygous db/+) mice (data not shown).
