Sentence examples for mice show profound from inspiring English sources

Furthermore, Nrf2 deficient mice show profound susceptibility to striatal lesions produced by the mitochondrial complex 2 inhibitor malonate [21].

Moreover, ADAMTS knockout mice show profound developmental defects demonstrating their unquestionable importance during vertebrate embryonic development.

This result is unexpected given that the 8 month old R26CT-CRE mice show profound spatial working memory deficits.

5-FU-treated mice show profound cell proliferation impairment, as demonstrated by ablated mitotic index in the duodenal crypts.

These mice show profound hearing impairment from P18, with significant differences in hearing thresholds between wild type and heterozygotes.

GluN1hypo mice show profound deficits in tests of short- and long-term memory, on both spatial and non-spatial learning tasks, as well as disruptions to naturalistic behaviors.

Although TMZ did not completely wipe out adult neurogenesis (as reported after irradiation), treated mice showed profound impairments in cognitive flexibility while learning the MWM, both before and after platform reversal.

Immunohistochemical staining (Fig. 2) with an anti-GluR2 antibody revealed that, when compared with the control mice (Fig. 2A C), the GluR2-cKO mice showed profound loss of GluR2 protein from cells in the CA1 region (Fig. 2F), little loss of GluR2 from the CA3 region (Fig. 2E) and no evident loss of GluR2 protein from the DG (Fig. 2D).

In addition, we show that Fenobam treatment of WT mice showed profound side effects in the motor coordination task.

In contrast, slices from cKO mice showed profound changes in excitability when perfused with 100 nM kainate (Fig.  7d f).

Occ +/+ and Occ +/− mice showed normal hearing thresholds (10 50 dB SPL), while Occ −/− mice showed profound deafness (hearing threshold, >70 90 dB SPL).