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Comparison of cytokine message in naïve pDCs from A/J and C3H mice revealed comparable levels of IL-6, TNFα, TGFβ1.
Preliminary pharmacokinetic analysis of serum samples from treated mice revealed comparable characteristics between SGN-40 and SGN-40G1v1 (data not shown).
A detailed flow cytometric analysis of the thymus, spleen and bone marrow from DKO and TKO chimeric mice revealed comparable alterations in particular leukocyte populations, such as elevated numbers of macrophages, mature T-cells (both CD4+CD8− and CD4−CD8+), and B cells that exhibited a memory cell phenotype.
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Quantification of ipsilateral projections between different mutants and control mice reveals comparable proportions of ipsilateral projections.
Measurement of striatal MPP+ levels in S100B+/+ and S100B−/− mice, however, revealed comparable results (Supplementary Table 3).
A comparable cross of Bax−/− and BCL-2tg mice revealed no comparable differences between BCL-2tg and Bax− / − BCL-2tg animals (Supplementary Table 3).
In accordance with an unaltered epidermal thickness, immunofluorescence (IF) staining of mouse back skin sections revealed comparable expression of the proliferation marker Ki67 in Cre-deficient control, Hdac1Δ/Δep and Hdac2Δ/Δep mice (Supplementary Figures S1E and F).
Similar expression trends across developmental stages were seen in both CYT-1 and CYT-2 transgenic mice; direct comparison between mice harboring the two transgenes at each stage revealed comparable expression levels.
Western blot analysis indeed revealed comparable levels of PrPc in all mouse strains tested (Fig. 5, data not shown).
However, we excluded the possibility that the higher susceptibility of PrPC-null mouse OHC was due to an overexpression of NMDAR at synapses, as we revealed comparable levels of interaction between PSD95 and GluN2A, and indirectly with GluN1, in wild-type and PrPC-null mouse hippocampi.
Histology not only emphasized the reduction in thymic size, but revealed comparable changes in structure and cellularity seen in the outbred perinatal lethal mice (Fig. 4A, B) [5], [7].
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