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We next examined whether the viruses that accumulated in infected mice retained the input-virus genome sequence at M847.
Specifically, at 14 days post-surgery, 87.5% of the operated SPARC−/− mice retained the blebs compared to 0% of the operated WT mice.
Subsequently, we found that CB-T cells that were reconstituted in NOD/SCID mice retained the ability to proliferate and differentiate.
However fibroblasts derived from paxillin knockout mice retained the ability to migrate [38], suggesting that paxillin expression is not a direct correlate with migration.
The density of viable GPT neurons in the unscarred dorsal pallium of ablated mice retained the same developmental pattern, but had a reliably different age distribution from that of controls.
Sequencing data indicated that the UV-irradiated p53+/- mice retained the non-mutated p53 allele, suggesting loss of heterozygosity did not play a role in the induction of this tumor [ 19].
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These mice retain the normal regulation of human MC1R and have a wild type, agouti, coat colour.
In the Tc1 mouse, tissue retention of Hsa21 is also mosaic, with 20 50% of cells in the hearts of adult Tc1 mice retaining the Hsa21 transchromosome.
For example, dopamine-deficient mice retain the ability to pick the most rewarding drink (sucrose compared with water) when presented in a discrimination task (Cannon and Palmiter, 2003).
However, resveratrol injection in the Tg-RSV mice retained 81.48% of the motor neurons compared with the Tg-Veh mice (438.75 ± 41.31 versus 796.25 ± 42.61, P < 0.01).
Although there was no difference in proliferating β-cells in the Harlequin mice, 3-fold more β-cells in the Hq mice retained in G2 phase of the cell cycle.
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