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PrPres Western blot profiles from 30 mice representative of the different sheep genotypes and of the three subpopulations of TgOvPrP4 mice were subjected to repeated analyses and quantification.
MCF10AT are pre-malignant, able to generate only small nodules in nude mice, representative of benign simple ducts, with < 25% of xenografts progressing to carcinomas [ 35, 36].
SPECT/CT movie of the kinetics of migration of adoptively transferred CD4+ T lymphocytes in recipient mice (representative of three mice per time point).
The tumours were selected from mice representative of the general phenotype of the transgene status, as demonstrated by haematoxylin and eosin-stained tumour sections.
A genoproteomic approach was used to assess polymorphism of the major milk proteins between SEG/Pas and C57BL/6J, two inbred strains of mice representative of Mus spretus and Mus musculus species, respectively.
Histograms show CD44, CD5, CD69 or TCRb expression on gated DP, CD4SP or CD8SP thymocytes from WT (solid gray) vs chino (red overlay) mice, representative of four separate experiments (n = 7 mice per group in total).
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In thus transplanted mice, representatives of all cell lineages derived from intestinal crypt stem cells (absorptive columnar, enteroendocrine, goblet and Paneth cells) showed expression of chromosomal markers characterizing donor BMD cells.
Data depict an individual mouse representative of more than three independent experiments with 10+ total mice.
Data depict an individual mouse representative of more than 30 total mice from 10+ independent experiments.
(A ) Thioflavin-S staining confirms absence of amyloid plaque deposition in 3 month-old PSAPP and age-matched PSAPP/Rag2 ko mice (representative images of cortical stainings are shown).
At both ages, mouse Foxa1 was predominantly expressed in the nuclei of atypical epithelium in TgTSPY9 /LADY mice and those of normal epithelial cells in the single-transgenic TgTSPY9/CD1 mice (representative images at 14 weeks of age in Figure 4B and F respectively).
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