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Autoimmune insulitis in NOD mice reflects a condition of disturbed immune homeostasis that involves deregulation of both effector (Teff) and regulatory T cells (Treg).
These findings support the notion that enhanced FAA in KO mice reflects a behavioral manifestation of a food-driven circadian oscillator and suggest that 5-HT2CRs gate food-anticipatory activity through mechanisms involving extrahypothalamic neural pathways.
Collectively, these data indicate that atrophy of the mammary fat pad in aging female VDR KO mice reflects a reduction in whole body fat stores secondary to enhanced energy expenditure.
Therefore, the hepatic copper deficiency in ob/ob mice reflects a localised process.
These combined data demonstrate that each of the changes in the B-cell compartment in WASp−/− mice reflects a B cell intrinsic defect.
This suggests that proinflammatory activation in the mammary glands of BALB-neuT664V-E mice reflects a general pattern of human breast cancer.
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To examine the possibility that FAA of KO mice reflects an hourglass mechanism, we subjected WT and KO mice to a restricted feeding paradigm with two additional days of total food deprivation following the 14 days of restricted feeding (Figure 4,5A D).
We speculate that the activity phenotype in D1R KO mice reflects an additional metabolic factor.
Therefore, the major phenotype we detect in myeloid pten -/- mice reflects an inability to mount an adaptive immune response that is able to induce joint pathology in these mice.
At present, it cannot totally be excluded that the failure to initiate spermatogenesis and the observed GC deficiency in adult SC Cx43KO mice reflects an altered state of SC maturation and a sign for functional immaturity of the SC, as proposed by Sridharan et al. (Sridharan et al., 2007a).
Therefore, we considered that results obtained using iv/iv mice reflect a consequence of hippocampal abnormality.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com