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Thirty male albino mice were divided equally into 3 groups, each of 10 animals; group 1, mice received normal saline solution (control group); group 2, mice received 5-fluorouracil 80 mg/kg b.wt./day intraperitoneally for 4 weeks (5-fluorouracil group); group 3, mice received 5-fluorouracil 80 mg/kg b.wt./day for 4 weeks with daily injection of vitamin C (12 mg/kg b.wt./day) for 4 weeks.
The remaining mice received normal water.
All mice received normal diet and were monitored daily by the Animal Care and Veterinary Service- ACVS) staff.
Under the conditions of ether anesthesia, the LPS group mice received LPS (Sigma-Aldrich Corps., St . Louis MO, USA, 5 mg/kg) by intratracheal injection; the control group mice received normal saline.
These mice received normal drinking water for 2 weeks, and then two groups were given distilled water containing 10% sucrose, three groups drank doxycycline 200 μg/ml and one group was given doxycycline 2 mg/ml; the doxycycline solutions were prepared in distilled water containing 10% sucrose.
Using bone-marrow chimeras, Chen and colleagues demonstrated that MSU-induced inflammation was not modified when normal wild-type mice received IL-1RI-/ or MyD88-/ bone marrow, but inflammation was attenuated when IL-1RI-deficient or MyD88-deficient mice received normal bone marrow [ 19].
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Furthermore, septic mice receiving normal saline experienced significantly more post-sinusoidal adhesion than septic mice receiving any other crystalloid fluid.
SUVmax (B/A), the primary indicator of effectiveness of radiosensitization, was 1.03 ± 0.03, 1.04 ± 0.04, and 1.24 ± 0.02 for the mice receiving normal saline, 1 mg of AGuIX, and 10 mg of AGuIX, respectively (Fig. 4).
Age-matched C57BL/6, HVEM-/ and LIGHT-/ mice receiving normal drinking water served as controls.
In fact, there were no differences in body weight between the EPO transfected high-fat fed mice and mice receiving normal chow (P = 0.23, n = 8).
After 40 days, body weight started to increase in the high-fat fed EPO group compared to mice receiving normal chow.
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mice received diluent
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