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Rats and mice reared on restricted amounts of food increase their lifespan by up to 40%.
Additionally, NOD.Igμ−/− mice reared on NOD dams did not develop T1D, indicating that autoantibody transmission to B-cell deficient NOD neonates is insufficient to trigger T1D.
Cortical bone in WT mice fed a HFD showed a significantly increased bone mineral density (BMD) compared with mice reared on a control diet (P<0.01).
Following a chronic HFD challenge, trabecular bone in WT mice showed a significantly altered microarchitecture resulting in thinner and more disorganized trabeculi, compared with mice reared on a control diet (Table 1).
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These movements back to the disc were associated with scanning, sometimes while the mouse reared on its hind legs, apparently checking that it was en route to the disc.
In the present study we compared mice reared and maintained on a low- (non-soy) and high-phytoestrogen containing soy-based feed.
We compared reproductive and metabolic characteristics in male and female mice reared and maintained on non-soy low-phytoestrogen feed or soy-based high-phytoestrogen feed.
Here, using an intercross between KK/HlJ (KK) and I/LnJ (I/L) mouse strains reared on standard mouse chow, a cross not previously evaluated for cholesterol levels, we report the confirmation of previously reported loci and the identification of additional, novel QTL controlling HDL and non-HDL cholesterol levels.
Therefore, the mice were reared on a high-fat diet, and their body weight, random blood glucose levels and insulin levels were measured; no differences were found between the two groups (Fig. 1f, g).
These germ-free mice, reared in sterile isolators in Gordon's lab, had 60percentt less fat than ordinary mice.
We observed that mice reared under hypoxic conditions gained less weight than mice reared in normoxia.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com