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Mutant mice ranged from 72 to 103 days of age.
Reduction of 5-HT in TPH2KO mice ranged from 67.5% (cerebellum) to 96.9% (striatum), while 5-HT reduction in DKO mice ranged from 94.4% (cerebellum) to 99.2% (cortex).
Plasma levels in CIT-treated mice ranged from 176 to 661 nM, with a mean of 383 nM (Fig. 1A).
IOP measurements in Vav2−/−Vav3−/− mice ranged from 11 40 mmHg between 7 weeks and 16 weeks of age.
The number of affected glands in CK19CreERT; LSL-KrasG12D mice ranged from 10 50% along the lesser curvature of the stomach with a decreasing frequency farther from the lesser curvature.
At 1 week post-STZ treatment, the measured glucose levels of SOD2-STZ, WT-STZ, WT, and SOD2 mice ranged from 283 598 mg/dl, 256 600 mg/dl, 143 177 mg/dl, and 172 189 mg/dl.
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Normal baseline PaCO2 levels in isoflurane anesthetized mice range from ~25 28 mmHG12,30.
Forest pocket mice range from southern Mexico to northern South America, where they live from sea level upward into mountains.
Silky and coarse-haired pocket mice range from western Canada and the United States into southern Mexico, where they inhabit open desert country.
To compare the glucose-lowering effect of HBK001 and linagliptin in a diabetic animal model, db/db mice ranging from 35-45 g in weight with fasting blood glucose levels >180 mg/dl, were selected for the experiments.
In a parallel experiment, KKAy mice, ranging from 45 55 g with fasting blood glucose levels >180 mg/dl, were selected and randomly divided into the same three groups as mentioned above.
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