Sentence examples for mice provided the from inspiring English sources

Until recently, transgenic mice provided the only experimental model capable of supporting the entire spectrum of LCR activities.

Targeted deletion of Mek5 and Erk5 in mice provided the first evidence for their essential role in development, leading to embryonic lethality at mid-gestation due to defective endothelial cell function and cardiovascular formation17,18,19,20.

Figure 1C shows that endogenous HGF was undetectable at embryonic day 16.5 and was still absent at postnatal day 7. Liver from neonatal HGF tg mice provided the positive control (Figure 1C, lower graph).

This hypothesis was supported by our analyses and we show that "signature transcripts" highly expressed in certain leukocyte populations (e.g., thioglycollate-elicited peritoneal Mφ) are often overwhelmingly elevated in hepatic tissue of mice provided the high fat diet.

The accumulation of Gaucher cells and GC in 9 V/null mice provided the opportunity to evaluate dose response at a tissue level and also to conduct comparative studies of the two GCases at three different doses; the dose range was 12-fold (5 60 U/kg/wk).

Generation of Tcf1 KO mice provided the first evidence of a Wnt signaling effect during T-cell development.

Thus, Myrf ICKO mice provide the necessary contrast to understand the contribution of oligodendrocyte remyelination to locomotor recovery.

As hypotheses are developed in human and cell culture systems, engineered mice provide the most tractable and accurate test of their validity in vivo.

Moreover, their ability to improve baicalin efficacy in anti-inflammatory and skin repair tests was confirmed in vivo in mice, providing the complete skin restoration and inhibiting all the studied inflammatory markers.

"This study in mice provides the first evidence that we may be on the threshold of being able to produce individualised vaccines directed against specific mutations present in a patient's tumour," Professor Harrington said.

The authors thank Britta Björkholm for performing experimental infection in mice, providing the in vivo passaged isolates, and critically reading the manuscript.